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The wife of Mexican drug kingpin Joaquin “El Chapo” Guzman was arrested Monday in the United States and accused of helping her husband run his multibillion-dollar cartel and plot his audacious escape from a Mexican prison in 2015.

A direct connection often exists between violence committed by drug cartels in Mexico and the act of an addict shooting up heroin in the bathroom of some Johnstown gas station.

Mexican drug cartels whose operatives once rarely ventured beyond the U.S. border are dispatching some of their most trusted agents to live an…